Telomere length and its relationship with age, oxidative stress, inflammation, metabolism, physical performance, cognition and quality of life in Thai subjects with normal body weight and overweight/obesity
Not Applicable
Recruiting
- Conditions
- ormal weight and overweight/obese individuals
- Registration Number
- TCTR20190417005
- Lead Sponsor
- Khon Kaen University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 136
Inclusion Criteria
Normal weight individuals
1)Age 20 †59 years
2)18.5 < BMI < 23 kg.m-2
3)No consumption of supplementation at least 3 months
4)No regular smoking and alcohol drinking
Overweight and obese individuals
1)Age 20 †59 years
2)23 ≤ BMI ≥ 34.9 kg.m-2
3)Not enrollment in any reducing weight program
4)No consumption of supplementation at least 3 months
5)No regular smoking and alcohol drinking
Exclusion Criteria
1)Pregnancy
2)Abnormal EKG
3)Diagnosis with hypertension
4)Diagnosis with dyslipidemia
5)Diagnosis with type 2 diabetes mellitus
6)Diagnosis with kidney and liver diseases
7)Chronic infectious diseases
8)Autonomic neuropathy
9) Bone fracture
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Telomere length 1 day Real time PCR,metabolism 1 day indirect calorimetry
- Secondary Outcome Measures
Name Time Method oxidative stress 1 day colorimetry based method,inflammation 1 day Particle enhanced immunoturbidimetry,Cardiorespiratory test 1 day 85% VO2peak by ergometer,cognition 1 day Montreal cognitive assessment,quality of life 1 day Short form 36,Strength test 1 day Hand grip dynanometer