The Analgesic Effect and Safety of Nefopam in Patient-controlled Analgesia after Cardiac Surgery: A Randomized, Double Blind, Prospective study
Not Applicable
Completed
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0000600
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 276
Inclusion Criteria
written informed consent from adult 276 patients, who were scheduled to undergo cardiac surgery were enrolled
Exclusion Criteria
Reasons for exclusion were: need for emergency surgery; failure to give informed consent; reduced left ventricular function (ejection fraction less than 40%); history of allergy to the PCA drugs; use of monoamine oxidase inhibitors; active seizure or history of seizure; glaucoma; high risk of urinary retention (i.e., urethral or prostate disease); severe renal or hepatic disease; critical pulmonary disease or history of respiratory disease; tachyarrhythmia or surgery for arrhythmia.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain was measured using a visual analog scale (VAS)
- Secondary Outcome Measures
Name Time Method postoperative incidence of tachycardia, sweating, sedation, respiratory depression, itching, nausea and vomiting;enquiring about patients’ satisfaction;times to extubation;stay in the intensive care unit (ICU)