MedPath

Molecular Modulation of the Growth Plate

Conditions
Growth Plate Injury
Registration Number
NCT03501589
Lead Sponsor
Mayo Clinic
Brief Summary

The researchers are trying to identify molecular mechanisms that control growth plate mediated limb growth and identify agents that can be used to enhance or slow growth.

Detailed Description

Not available

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Skeletally immature children/adults undergoing surgical procedures where growth plate cartilage is removed as a normal part of their procedure; or patients undergoing surgical procedures where bone is removed as a normal part of their procedure.
Exclusion Criteria
  • Skeletally mature children/adults

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
RNA expressionEnd of Study (1/2019

Measure RNA levels in growth plate tissue samples (ng/mL)

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Mayo Clinic'

πŸ‡ΊπŸ‡Έ

Rochester, Minnesota, United States

Mayo Clinic'
πŸ‡ΊπŸ‡ΈRochester, Minnesota, United States

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

Β© 2025 MedPath, Inc. All rights reserved.