Postoperative Residual Paralysis After Cardiac Surgery
- Conditions
- Postoperative Residual Curarization
- Registration Number
- NCT03291184
- Lead Sponsor
- Onze Lieve Vrouw Hospital
- Brief Summary
The main objective of this study is to describe the incidence of postoperative residual paralysis (mean train-of-four \<90%) when weaning from the ventilator in patients admitted to the Intensive Care Unit (ICU) after elective cardiac surgery. Train-of-four monitoring is a widely used term for the peripheral nerve stimulation used in neuromuscular blockade monitoring. When the patient is ready for weaning from the ventilator, an ICU doctor will perform a measurement of the train-of-four at the thumb with a neuromuscular transmission monitor. Every value below 90% will be considered as residual paralysis and treated appropriately by means of a reversal agent.
- Detailed Description
Postoperatively, in the ICU, readiness-for-weaning is based on ICU doctor-nurse-driven institutional weaning guidelines: 6 hours after arrival in the ICU, a patient who is normothermic, hemodynamically stable, has normal blood gasses and absence of residual bleeding. The ICU nurse caring for the patient will start weaning the patient from the ventilator, following these departmental guidelines.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 93
- patients admitted to the ICU after elective cardiac surgery
- emergency cardiac surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method postoperative residual curarisation 6 hours after arrival in the ICU mean train-of-four \<90% as measured by neuromuscular blockade monitoring
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
OLV Hospital
🇧🇪Aalst, Belgium