Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata
- Registration Number
- NCT03898479
- Lead Sponsor
- Concert Pharmaceuticals
- Brief Summary
The overall objectives of the study are to evaluate long-term safety of CTP-543 and to assess long-term effects of CTP-543 on treating hair loss in adult patients with chronic, moderate to severe alopecia areata.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 1000
- Have completed 24 weeks of treatment in a previous qualifying CTP-543 clinical trial
- Active scalp inflammation, psoriasis, or seborrheic dermatitis requiring topical treatment to the scalp, significant trauma to the scalp, or untreated actinic keratosis
- Females who are nursing, pregnant, or planning to become pregnant while in the study, and for 30 days after last dose of study medication
- Donation of blood at any point throughout the study and for 30 days after last dose of study medication
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description CTP-543 CTP-543 Patients who previously completed a qualifying CTP-543 clinical trial
- Primary Outcome Measures
Name Time Method Number of Participants with Adverse Events as a Measure of Safety 332 weeks Effect of CTP-543 on treating hair loss as measured by the Severity of Alopecia Tool (SALT) 332 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (89)
Total Skin and Beauty Dermatology Center
🇺🇸Birmingham, Alabama, United States
Alliance Dermatology & MOHS Center
🇺🇸Phoenix, Arizona, United States
Center for Dermatology and Plastic Surgery/CCT Research
🇺🇸Scottsdale, Arizona, United States
Johnson Dermatology
🇺🇸Fort Smith, Arkansas, United States
Northwest Arkansas Clinical Trials Center, PLLC
🇺🇸Rogers, Arkansas, United States
Kern Research Inc.
🇺🇸Bakersfield, California, United States
Hope Clinical Research
🇺🇸Canoga Park, California, United States
California Dermatology & Clinical Research Institute
🇺🇸Encinitas, California, United States
University of California, Irvine
🇺🇸Irvine, California, United States
Dermatology Research Associates
🇺🇸Los Angeles, California, United States
Scroll for more (79 remaining)Total Skin and Beauty Dermatology Center🇺🇸Birmingham, Alabama, United States