A clinical study of Protective effect of Fu's Subcutaneous Needling intervention on diaphragmatic function in patients with severe stroke under mechanical ventilatio

Phase 1

• Conditions: severe stroke

• Registration Number: ITMCTR2100005259
• Lead Sponsor: Shandong Provincial Third Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Patients who meet the diagnostic criteria for stroke in the Guidelines for the Prevention and Treatment of Cerebrovascular Diseases in China, and are confirmed by CT or MRI scans of the brain, and receive MV treatment;
2. 20-90 days after stroke, the patient's vital signs are stable, and the GCS score is >=9;
3. Aged 18 to 80 years;
4. The family members signed the informed consent form and agreed to participate in the study.

Exclusion Criteria

1. Combined with primary diseases that affect muscle strength: such as brainstem infarction, brainstem hemorrhage, spinal cord injury, myasthenia gravis, etc.;
2. Color Doppler ultrasound shows pleural effusion, pneumothorax, pleural adhesion, etc., or the diaphragm cannot be detected by ultrasound due to the disease;
3. Combined with respiratory diseases such as pulmonary interstitial fibrosis, lung tumor, active pulmonary tuberculosis;
4. Severe malnutrition, liver and kidney failure.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mechanical ventilation time;

Secondary Outcome Measures

Name	Time	Method
Intensive Care Unit hospital stay;The incidence of ventilator-associated pneumonia;Offline success rate;Diaphragm thickening fraction;Respiratory efficiency;Diaphragmatic Shallow Rapid Breathing Index;diaphragm excursion;Intensive Care Unit mortality rate;Acute Physiology and Chronic Health Status Score II.;