NCT02684552已完成不适用
Physiotherapist in Charge of the Study
Karolinska University Hospital4 个研究点 分布在 1 个国家目标入组 8 人开始时间: 2016年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 8
- 试验地点
- 4
- 主要终点
- Transcutaneous level carbon dioxide
研究概览
简要总结
Patients with cystic fibrosis older than 18 years will performance a Bruce test with non invasive ventilation (once) after 30 minutes they perform the same test with oxygen supplementation.
Measurements: Transcutaneous level off carbon dioxide, saturation, puls and dyspnea scale.
详细描述
measurements before and after the test: transcutaneous level off carbon dioxide, saturation, respiratory rate, dyspnea scale.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects with Cystic Fibrosis at Stockholm Cystic Fibrosis center
- •> 18 years of age
- •Forced expiratory volume in one second (FEV1) between 20 and 69% of predicted value
- •Developed alveolar hypoventilation at the physical performance test
- •Use oxygen supplementation during aerobic training
排除标准
- •Symptomatic upper airway infection characterized by fever less than 1 month before entering the study
- •Cognitive dysfunction
- •Cardio-respiratory instability
- •Infection with Burkholderia cepacia complex
- •Gastroesophageal reflux
- •History of pneumothorax
- •Massive hemoptysis.
结局指标
主要结局
Transcutaneous level carbon dioxide
时间窗: 10 min measurement
Physiological parameter
次要结局
未报告次要终点
研究者
Cecilia Rodriguez
Physiotherapist
Karolinska University Hospital
研究点 (4)
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