Non Invasive Ventilation During Physical Training in Cystic Fibrosis
Not Applicable
Completed
- Conditions
- Cystic Fibrosis
- Registration Number
- NCT02684552
- Lead Sponsor
- Karolinska University Hospital
- Brief Summary
Patients with cystic fibrosis older than 18 years will performance a Bruce test with non invasive ventilation (once) after 30 minutes they perform the same test with oxygen supplementation.
Measurements: Transcutaneous level off carbon dioxide, saturation, puls and dyspnea scale.
- Detailed Description
measurements before and after the test: transcutaneous level off carbon dioxide, saturation, respiratory rate, dyspnea scale.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 8
Inclusion Criteria
- Subjects with Cystic Fibrosis at Stockholm Cystic Fibrosis center
- > 18 years of age
- Forced expiratory volume in one second (FEV1) between 20 and 69% of predicted value
- Developed alveolar hypoventilation at the physical performance test
- Use oxygen supplementation during aerobic training
Exclusion Criteria
- Symptomatic upper airway infection characterized by fever less than 1 month before entering the study
- Cognitive dysfunction
- Cardio-respiratory instability
- Infection with Burkholderia cepacia complex
- Gastroesophageal reflux
- History of pneumothorax
- Massive hemoptysis.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Transcutaneous level carbon dioxide 10 min measurement Physiological parameter
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Maria Cecilia Rodriguez Hortal
🇸🇪Stockholm, Sweden
Cecilia Rodriguez
🇸🇪Stockholm, Sweden
Maria Cecilia Rodriguez Hortal🇸🇪Stockholm, Sweden