Effect of various parameters of complete blood count in patients with preeclampsia
Not Applicable
- Conditions
- Health Condition 1: O149- Unspecified pre-eclampsia
- Registration Number
- CTRI/2020/09/027531
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of preeclampsia meeting following criteria
Systolic blood pressure >140 and/or DBP >90 mm of Hg on two occasions at least 4 hours apart; and proteinuria of >1+ on dipstick or 300 mg/day, after 20 week of gestation
Exclusion Criteria
Chronic hypertension
Overt diabetes/GDM type A2
Renal Disease
Fever within previous 1 week of diagnosis
Collagen vascular disorder
Rheumatoid arthritis
Known autoimmune disorders
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Values of NLR,MLR,PLR,MPV,PDW in patient of preeclampsia <br/ ><br>- Correlation of these markers with severity of preeclampsia <br/ ><br> <br/ ><br>NLR: Neutrophil to lymphocyte ratio <br/ ><br>MLR: Monocyte to lymphocyte ratio <br/ ><br>PLR: Platelet to lymphocyte ratio <br/ ><br>MPV: Mean platelet volume <br/ ><br>PDW: Platelet distribution widthTimepoint: At recruitment and at 28, 32 and 36 weeks (as applicable according to the gestational age at recruitment) and at delivery
- Secondary Outcome Measures
Name Time Method 1.Maternal outcome: Eclampsia, HELLP syndrome, Mode of delivery <br/ ><br>2.Fetal outcome: fetal growth restriction,intrauterine fetal death,prematurity and low birth weight <br/ ><br>3.Levels of other haematological markers such as RDW, Plateletcrit, absolute values of platelet count in preeclampsia <br/ ><br> <br/ ><br>Timepoint: - Haematological markers at recruitment and at 28, 32 and 36 weeks (as applicable according to the gestational age at recruitment) and at delivery <br/ ><br>- Maternal and fetal outcomes at delivery <br/ ><br>