Comparison between two antibiotic schemes to improve the results in patients with premature rupture of membranes

Not Applicable

• Conditions: Antibiotic treatment in patients with preterm premature rupture of membranes, less than 33 weeks; Pregnancy and Childbirth

• Registration Number: ISRCTN25718638
• Lead Sponsor: Hospital Padre Hurtado

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-08-29
• Last Update Posted: 11 September 2023
• Study Completion: 2024-12-20

Recruitment & Eligibility

• Status: Ongoing
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

1. Pregnant women between 24+0 and 32+6 weeks
2. Diagnosis of premature rupture of membranes
3. Negative admission amniocentesis for intra-amniotic infection

Exclusion Criteria

1. Patients outside the gestational age range
2. Positive admission amniocentesis for intra-amniotic infection
3. Concomitant infectious process that requires antibiotics (e.g. COVID-19; pyelonephritis, bacterial pneumonia, tonsillitis or another that requires antibiotic use)
4. Patient with a history of recent use of antibiotics in the last 10 days
5. Patient allergic to any of the antibiotics proposed in the different schemes
6. Patient undergoing multiple pregnancy
7. Patients who do not wish to participate and therefore do not sign the informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified