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Clinical Trials/NCT05342922
NCT05342922
Completed
Not Applicable

Comparison of Ultrasound and Anatomical Land-mark Method in Spinal Anesthesia for Elective Cesarean Section in Obese Parturients With BMI ≥ 40 kg/m2. A Randomized Controlled Trial

Karaman Training and Research Hospital1 site in 1 country80 target enrollmentMay 23, 2022
ConditionsMorbid Obesity

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Morbid Obesity
Sponsor
Karaman Training and Research Hospital
Enrollment
80
Locations
1
Primary Endpoint
The success rate of first puncture
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who will undergo elective cesarean section.

The primary objective in this study is the rate of successful dural puncture at the first attempt. It was assumed that ultrasound could facilitate neuraxial blockade in grade 3 morbidly obese pregnant women according to the Who classification, whose topographic anatomy is difficult.

Detailed Description

Spinal anesthesia is the most commonly used anesthesia method for elective cesarean deliveries. Anesthesiologists may have difficulties in determining the poorly palpable surface landmarks in morbidly obese pregnant women. Manual palpation technique, which is preferred in neuraxial anesthesia, may be difficult in obese pregnant women due to the difficulty in identifying bone landmarks. Neuraxial ultrasound examination before spinal anesthesia may help spinal anesthesia performance and decrease number of attempts in obese parturients. This study will be conducted as a single-center, prospective, randomized, double-blinded trial in a university hospital. Patients scheduled for elective cesarean will be screened for enrollment in the study. Patient, the anesthetist administering spinal anesthesia and evaluating the data were blind to the distribution of patient groups.Ultrasonographic examinations were performed by a single investigator trained in this technique who performed more than 150 ultrasound-guided neuraxial blocks.

Registry
clinicaltrials.gov
Start Date
May 23, 2022
End Date
January 24, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Karaman Training and Research Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Parturient who will receive selective cesarean delivery under spinal anesthesia
  • ASA 2-3 scheduled for elective sections
  • BMI≥40 kg/m2
  • normal singleton pregnancy
  • ≥37 weeks of gestation

Exclusion Criteria

  • Multiple gestations
  • Emergency C-section
  • exist contraindications of spinal anesthesia
  • Local anesthetics allergy
  • BMI\<40 kg/m2
  • history of lumbar spinal diseases and lumbar surgery
  • Parturient refusal

Outcomes

Primary Outcomes

The success rate of first puncture

Time Frame: 30 minute

Success on a single-puncture attempt will be defined as reaching the subarachnoid space on the first insertion of the needle.

Secondary Outcomes

  • Number of skin punctures(30 minute)
  • Time taken for spinal injection(30 minute)
  • Failure rate of spinal anesthesia(120 minute)
  • The procedure duration time(30 minute)
  • Time interval to determine needle insertion site(30 minute)
  • incidence of postoperative headache(72 hour)
  • Incidence of hypotension(2 hour)
  • Number of puncture levels(30 minute)
  • Number of needle pass(30 minute)
  • Patient satisfaction The procedure duration(30 minute)
  • incidence of complications during puncture(30 minute)
  • dermatome level of sensory block [ Time Frame: 10 minutes after spinal anesthetic injection ](20 minute)

Study Sites (1)

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