Erythropoietin and Magnesium Sulphate in Hypoxic Ischaemic Encelpalopathy
Not Applicable
- Conditions
- Neonatal DiseasesPregnancy and Childbirth
- Registration Number
- PACTR201812814507775
- Lead Sponsor
- Ezenwa Beatrice
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
All term newborns (= 37weeks gestation) diagnosed of perinatal asphyxia at admission and who are <72 hours of age.
Evidence of Perinatal depression based on delayed cry at birth and at least one criteria on Sarnat and Sarnat HIE grading
Exclusion Criteria
Severe congenital anomalies
Preterm babies
Infants >72 hours of age at time of presentation /consent
Those in which consent could not be obtained
Evidence of sepsis (confirmed according to unit protocol)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Survival at discharge or Death within the first two years of life and<br>Neurodevelopmental impairment at 6, 12, 18 and 24 months of age
- Secondary Outcome Measures
Name Time Method Association between the levels of NRBC and NRBC/100WBC with neonatal outcome<br>Safety of the medications based on the presence or absence of any adverse event