Comparative Study Of Recovery Characteristics Using Intraoperative Dexmedetomidine With Remifentanil In Patients Undergoing Elective Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To compare recovery characteristics like Richmond Agitation sedation scale(RASS)
研究概览
简要总结
After getting approval from college research committee[CRC] AND Institutional ethical committee[IEC],those patients meeting the inclusions criteria will be enrolled
Randomization will be done by computer generated random random table number and 80 patients will be assigned into two groups, Group DM and Group RF, 40 patients in each group.
Group DM : Dexemedetomidine loading dose 1mcg/kg followed by infusion dose 0.5mcg/kg/hr
Group RF : remifentanyl loading dose 1mcg/kg followed by infusion dose 0.5mcg/kg/min
Induction of anaesthesia and tracheal intubation of anaesthesia will be used as per patient characteristics and institutional protocol
Intraoperative monitoring [HR,SBP,DBP,MAP,PR,PI,SPO2] will be done as per instuitional protocol.
After Extubation, patients will be shifted post anaesthesia care unit
After they achieved Aldrete score [<9], then shift the patients PACU to ward
NRS SCORE :
MEASURED 1ST 30mins and hourly for the first 2hours and then at 4hourly interval till 24hour
All pre operative and post operative data collected will be analyzed
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient posted for Elective Laparoscopic Cholecystectomy.
- •Patient giving written and informed consent.
- •American Society of Anesthesiologist (ASA) physical status I-II Age group of 18-60 years old.
- •BMI 18.5kg/m2 to 24.9kg/m2.
排除标准
- •Patient history of allergy to opioids, alpha-2 receptor drugs.
- •History of alcohol and drug abuse.
- •Pregnant patients.
结局指标
主要结局
To compare recovery characteristics like Richmond Agitation sedation scale(RASS)
时间窗: 0mins,15mins,30mins,45min,1hour,2hour,4hour,8hour,12hour,16hour,20hour,24hour
To compare Pain using Numerical rating score(NRS) in both the groups.
时间窗: 0mins,15mins,30mins,45min,1hour,2hour,4hour,8hour,12hour,16hour,20hour,24hour
To compare time from post anaesthesia care unit to ward in both the groups.
时间窗: 0mins,15mins,30mins,45min,1hour,2hour,4hour,8hour,12hour,16hour,20hour,24hour
次要结局
- To compare hemodynamics parameters in both the groups.(To compare total post operative analgesic consumption in both the groups.)
研究者
Dr subidhi devadiya
teerthanker mahaveer medical college and research centre