Medical assessment of adverse health outcomes in Dutch childhood cancer survivors; a nationwide project; SKION LATER Q2008 onderzoek - Reproductive potential in male survivors of childhood cancer

Completed

• Conditions: late effects; long-term effects; 10014701; 10013356

• Registration Number: NL-OMON47702
• Lead Sponsor: Stichting Kinderoncologie Nederland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 2700

Inclusion Criteria

adult (> 18 yrs of age) male patients who were treated for childhood cancer
(before age 18) in one of the Pediatric Oncology Centers between 1960 and 2001
and who survived for at least 5 years after diagnosis will be included in the
SKION LATER study. Participating centres are located in Amsterdam (VU
University Medical Center (VUMC)), Groningen (Children's Cancer Center/
University Medical Center Groningen (UMCG)), Rotterdam (Rotterdam Erasmus
MC-Sophia (REMC-S), Nijmegen (University Medical Center Nijmegen (UMCN)),
Leiden (Leiden University Medical Center (LUMC) and Utrecht (Princess Máxima
Center for Pediatric Oncology (PMC)).

Exclusion Criteria

diagnosis of childhood cancer with survival less than 5 years, age at diagnosis
>17 years or diagnosis while residing in foreign country; females

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>prevalence of subfertility diagnostic value of inhibin B and AMH reproductive<br /><br>history and health of offspring </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>