Bowel Sounds Analysis in Paediatric Inflammatory Bowel Disease: Relationship With wPCDAI

Not Applicable

Active, not recruiting

• Conditions: Intestinal Inflammation; Crohn Disease; Bowel Sounds
• Interventions: Other: Abdominal auscultation

• Registration Number: NCT05955963
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

The precise and noninvasive evaluation of disease activity among patients with Crohn's disease is not easy, especially for children. It deals with clinical, biological, histological and radiological parameters.

Bowel sounds (BS) when evaluated by a stethoscope are modified by several factors including surgery, infection, drugs or intestinal inflammation. These factors can interact on intestinal motricity. There is a direct relationship between gastrointestinal motility and characteristics of BW. The study of BS using a stethoscope is a simple method, although operator dependent and subjective,with a wide inter and intraindividual variability. Some studies among adults showed interest in the spectral analysis of BS to assess gastrointestinal motility. This more precise and reproducible method is not operator dependent.

To date, no such study has evaluated the correlation between disease activity and the spectral pattern of BS.

of this project is to assess the correlation between disease activity and the spectral pattern of BS in pediatric Crohn's disease.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-24
• Status Verified: 2023-07
• Study First Submitted: 2023-07-13
• Study First Submitted QC: 2023-07-13
• Last Update Submitted: 2023-07-13
• Study First Posted: 2023-07-21
• Last Update Posted: 2023-07-21
• Primary Completion: 2023-09-02
• Study Completion: 2024-06-04

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 49

Inclusion Criteria

• Crohn's Disease
• Age between 4 and 17 years
• Follow-up at CHU Amiens-Picardie

Exclusion Criteria

• Other diseases than Crohn's or treatments affecting the gastrointestinal tract, recent (< 3 months) surgery or refusal to participate (parents or children)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
paediatric inflammatory bowel disease	Abdominal auscultation	-

Primary Outcome Measures

Name	Time	Method
evaluation of wPCDAI	one day	wPCDAI is WEIGHTED PAEDIATRIC CROHN'S DISEASE ACTIVITY INDEX
evaluation of frequency of bowel sounds	one day
correlation between wPCDAI and frequency of bowel sounds	one day	wPCDAI is WEIGHTED PAEDIATRIC CROHN'S DISEASE ACTIVITY INDEX

Trial Locations

Locations (1)

CHU Amiens; 🇫🇷 Amiens, France