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Strong Hearts: A Remote, App-Enabled, Exercise Program for Patients With Congenital Heart Disease (Strong Hearts App)

Not Applicable
Active, not recruiting
Conditions
Congenital Heart Disease
Interventions
Behavioral: Strong Hearts Exercise Program
Registration Number
NCT05853705
Lead Sponsor
Duke University
Brief Summary

The overall goal of this program is to create a remote, mobile application enabled exercise program for patients with Congenital Heart Disease (CHD). Pilot trials will consist of a remote exercise program with app-embedded exercise modules designed to promote and encourage safe and healthy exercise habits across a range of CHD anatomies. This app-enabled program will allow for real time data collection integrating wearable devices, as well as compliance and safety monitoring to enhance research capabilities. The app-enabled program will be versatile and may be applied in the future to patients with non-cardiac conditions.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Repaired or unrepaired Congenital Heart Disease (CHD)

  • Between ages 10 and 50, inclusive, at time of consent

  • Android or Apple smartphone that meets the operating systems below with the ability to download applications from either Google Play or the Apple store

    • Android: 6.0 or higher
    • Apple: iPhone Operating System (iOS) 13 or higher
Exclusion Criteria
  • Physical or mental disabilities preventing exercise participation
  • Uncontrolled systemic hypertension (symptomatic or greater than Stage 2 hypertension while on therapy)
  • Poorly controlled arrhythmia
  • Clinically unstable heart failure
  • Known pregnancy at the time of enrollment

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Exercise GroupStrong Hearts Exercise ProgramParticipants will participate in a remote, app-enabled exercise program consisting of strength and aerobic exercises for four to twelve weeks. They will perform the exercises 3-5 times a week at home guided by exercise videos in the app. The exercise sessions will increase in frequency throughout the training regimen. The videos will include athletes demonstrating how to perform each exercise safely, and provide tips for optimal form and breathing. Participants will wear wearable fitness trackers and monitor their heart rates during exercise sessions.
Primary Outcome Measures
NameTimeMethod
Change in peak rate of oxygen volume consumption (VO2) on Cardiopulmonary Exercise TestingBaseline, up to 12 weeks
Secondary Outcome Measures
NameTimeMethod
Change in Pediatric Cardiac Quality of Life Inventory1 year

The Pediatric Cardiac Quality of Life Inventory generates 3 scores (total, disease impact subscale, and psychosocial impact subscale). Each subscale has a maximum of 50 points and their sums yields the total score. Higher scores indicate better perceived health-related quality of life.

Change in sit-to-stand testBaseline, up to 12 weeks
Change in Short Form 36 (SF-36) Health Survey1 year

The Short Form 36 Health Survey consists of 8 subscales (physical functioning, role limitations due to physical health, role limitations due to emotional problems, energy/fatigue, emotional well-being, social functioning, pain, and general health). The survey will be scored using the two step RAND scoring process. The first step scores each question on a scale from 0 (worst) to 100 (best) and represents the percentage of total possible score achieved. The second scoring step, takes the average of all the questions in each subscale to create the 8 scores.

Change in secondary Cardiopulmonary Exercise Testing outcome measuresBaseline, up to 12 weeks

Trial Locations

Locations (1)

Duke University Medical Center

🇺🇸

Durham, North Carolina, United States

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