Pleural Manometry During Thoracocentesis in Patients With Malignant Pleural Effusion: How Much Fluid Should we Drain?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- the pleural pressure
研究概览
简要总结
The study aiming to measure the pleural pressure during thoracocentesis in patients with pleural effusion and the value of their measurement in both diagnostic and therapeutic decisions.
详细描述
This prospective controlled trial study will be performed between July 2019 and December 2020. the investigators will enroll patients with large volume pleural effusion referred to our Cardiothoracic Department, Faculty of Medicine, Ain Shams University to perform therapeutic thoracentesis. All the patients will sign an informed consent for pleural pressure monitoring during and after therapeutic thoracentesis.
The study aiming to measure the pleural pressure during thoracocentesis in patients with pleural effusion and the value of their measurement in both diagnostic and therapeutic decisions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age between 18 and 85 years,
- •pleural effusion occupying at least one-third of the ipsilateral hemithorax in P-A chest radiograph (CXR)
- •no contraindications for therapeutic thoracentesis
- •general health condition allowing prolonged procedure of therapeutic thoracentesis.
排除标准
- •patients with very small amounts of pleural effusion
- •patients on mechanical ventilation
- •patients using anticoagulant therapy
- •patients refusing to be subjected to thoracocentesis.
结局指标
主要结局
the pleural pressure
时间窗: Continous monitoring during the whole session of thoracocentesis
To measure the pleural pressure(mmHg) during thoracocentesis in patients with pleural effusion using a simple water pleural manometer
次要结局
未报告次要终点
研究者
Aly Sherif Hassaballa
Clinical Professor
Ain Shams University