A study to measure the zinc level in blood of children with severe pneumonia and to find out the effect of zinc supplementation ( given for 14 days ) in those children on recurrence or further attacks of pneumonia in the next 3 months.
Phase 3
Completed
- Conditions
- Health Condition 1: null- Pneumonia
- Registration Number
- CTRI/2012/11/003105
- Lead Sponsor
- Dr Aditi Baruah
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 560
Inclusion Criteria
children aged 2 â?? 60 months with severe pneumonia [who satisfy the World Health Organization (WHO) case definition of severe pneumonia ie Fever, Cough, Fast breathing (>= 50 / min in 2 mo â?? 12 mo and >= 40 / min in 1 â?? 5 yrs) and chest indrawing , requiring admission
Exclusion Criteria
1) Very severe pneumonia as per WHO case definition
2)Severe acute malnutrition
3)Child with Tuberculosis (of any system)
4)Known case of congenital heart disease
5)Present episode associated with allergic diseases or asthma
6)History of intake of Zinc in past three months
7)With an associated clinical diagnosis of diarrhea
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method i) Blood collection for zinc estimation <br/ ><br> ii)Time taken in hours for clinical resolution <br/ ><br>Timepoint: Blood collection within 24 hours
- Secondary Outcome Measures
Name Time Method i)Duration of hospital stay in completed days <br/ ><br>ii)Total number of episodes of fever and cough with fast breathing (50 or more per min in 2 mo â?? 12 mo and 40 or more per min in <br/ ><br>1 â?? 5 yrs) in next three months <br/ ><br> <br/ ><br>Timepoint: i) Duration of hospital stay from admission to discharge <br/ ><br>ii) No of episodes of pneumonia from discharge to 3 months