Comparison of two drugs for better blood pressure and heart rate control during surgery
Not Applicable
Completed
- Conditions
- Health Condition 1: null- scheduled for laparoscopic cholecystectomy under general anaesthesia.
- Registration Number
- CTRI/2018/06/014453
- Lead Sponsor
- maulana azad medical college
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 48
Inclusion Criteria
•ASA physical status I and II patients in the age-group 18-50 undergoing laparoscopic cholecystectomy.
Exclusion Criteria
•History suggestive of allergy to either study drug.
•History suggestive of chronic use of antacids.
•Chronic alcoholics
•BMI >=30 kg/m2
•Known case of diabetes, chronic hypertension, cardiac disease.
•Known renal or hepatic insufficiency.
•Known case of neuromuscular disorders.
•Anticipated difficult airway
•Pregnant patients
•Patients at risk of aspiration i.e. full stomach, GERD, hiatus hernia etc.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean Arterial PressureTimepoint: T0: Baseline (after bolus of study drug & prior to administration of fentanyl) <br/ ><br>T1: Just before PLMA insertion <br/ ><br>T2 (i), T2 (ii), T2 (iii): 1, 2, 3 minutes after PLMA insertion <br/ ><br>T3: At peritoneal insufflation <br/ ><br>T4: 5 minutes after starting peritoneal insufflation <br/ ><br>T5: Before making 30â?? RTP <br/ ><br>T6: 5 minutes after 30â?? RTP <br/ ><br>T7: 5 minutes after flat position <br/ ><br>T8: 5 minutes after peritoneal deflation <br/ ><br>T9: Following removal of PLMA <br/ ><br>T10: At admission to PAC
- Secondary Outcome Measures
Name Time Method ï?? SBP <br/ ><br>ï?? DBP <br/ ><br>ï?? HR <br/ ><br>ï?? Sedation Score <br/ ><br>Timepoint: T0: Baseline (prior to administration of fentanyl) <br/ ><br>T1: Before PLMA insertion <br/ ><br>T2 (1 ),T2(2),T2(3): 1,2,3 minutes after PLMA insertion <br/ ><br>T3: Before peritoneal insufflation <br/ ><br>T4: 5 minutes after peritoneal insufflation <br/ ><br>T5: Before making 30â?? RTP <br/ ><br>T6: 5 minutes after 30â?? RTP <br/ ><br>T7: 5 minutes after flat position <br/ ><br>T8: 5 minutes after peritoneal deflation <br/ ><br>T9: Following removal of PLMA <br/ ><br>T10: At admission to PACU <br/ ><br>