PECO Air Purification in Hospital Rooms to Improve Health Outcomes for Pediatric Respiratory Distress

Not Applicable

Completed

• Conditions: Pneumonia; Asthma; Respiratory Distress Syndrome
• Interventions: Device: Photo Electrochemical Oxidation (PECO) for Air Purification

• Registration Number: NCT03647397
• Lead Sponsor: Molekule

Brief Summary

This study will investigate the efficacy of a novel air purification technology, Photo Electrochemical Oxidation (PECO), has on pediatric patients hospitalized for respiratory distress. The study will take place at Mercyhealth Hospital - Rockton Avenue where all 23 pediatric rooms will be outfitted with portable PECO air purifying units. The main outcomes are the length of stay and progression to ICU, which will be compared with historical controls.

Detailed Description

The goal of this study is to assess whether using PECO to purify air in a hospital can improve health outcomes for pediatric patients with respiratory distress.

The results of this study will be used in three primary ways:

1. As evidence to support an installation of PECO in hospital HVAC systems to improve the standard of care for patients with respiratory distress

2. Towards dissemination efforts through publication in a peer-reviewed journal and presentation at national and international conferences

3. For informing healthcare providers and stakeholders

There are no plans to repeat this study with other hospital partners

Study Timeline

• Study Start: 2018-08-08
• Study First Submitted: 2018-08-20
• Study First Submitted QC: 2018-08-23
• Study First Posted: 2018-08-27
• Primary Completion: 2018-12-31
• Study Completion: 2018-12-31
• Status Verified: 2019-05
• Last Update Submitted: 2019-05-15
• Last Update Posted: 2019-05-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 274

Inclusion Criteria

All pediatric patients who are admitted to the Mercyhealth Hospital - Rockton Avenue following the Start Date and have infectious or non-infectious respiratory distress as defined by the following ICD codes will be included in the study:

• J00-J06: Acute upper respiratory infections
• J09-J18: Influenza and pneumonia
• J20-J22: Other acute lower respiratory infections
• J30-J39: Other diseases of upper respiratory tract
• J40-J47: Chronic lower respiratory diseases
• J60-J70: Lung diseases due to external agents
• J80-J84: Other respiratory diseases principally affecting the interstitium
• J85-J86: Suppurative and necrotic conditions of the lower respiratory tract
• J90-J94: Other diseases of the pleura
• J95-J95: Intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified

Exclusion Criteria

• Any patient admitted to the NICU
• Patients in the ER only
• Any patient with non-respiratory conditions
• Adults

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
PECO	Photo Electrochemical Oxidation (PECO) for Air Purification	All pediatric patients admitted for respiratory distress will have the intervention of Photo Electrochemical Oxidation (PECO) for Air Purification.

Primary Outcome Measures

Name	Time	Method
Length of stay	5 months	Total length of hospital stay for patient

Secondary Outcome Measures

Name	Time	Method
Readmission rate	1 months	Rate of readmission within 30 days of discharge

Trial Locations

Locations (1)

Mercyhealth Hospital - Rockton Avenue; 🇺🇸 Rockford, Illinois, United States