ITMCTR2000003262RecruitingPhase 1
Study on the central mechanism of analgesic effect of Tuina on knee osteoarthritis based on multimodal MRI
Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine0 sitesStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 1
- Status
- Recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional study
Eligibility Criteria
- Ages
- 50 to 70 (—)
- Sex
- All
Inclusion Criteria
- •Inclusion criteria of patients with knee osteoarthritis
- •1. 50-70 years old;
- •2. It was diagnosed as osteoarthritis of knee joint and agreed to participate in this experiment;
- •3. All of them are right handed;
- •4. KL Level 2 or 3;
- •5. The pain time of knee joint is more than or equal to 3 months;
- •6. Agree and sign the informed consent.
- •Inclusion criteria for healthy volunteers
- •1. Right handedness;
- •2. The age range is 50-70 years old;
- •3. No history of chronic pain;
- •4. In the past 1 month, he did not receive medication, physical therapy or massage therapy;
- •5. Understand the process of the study, agree and sign the informed consent.
Exclusion Criteria
- •1. Patients taking analgesics or anti-inflammatory analgesics within the past 1 month;
- •2. Patients who received any other treatment within the past month;
- •3. Pregnant or lactating women;
- •4. Patients with mental disease, neurological disease, infectious disease, gastrointestinal disease, cardiovascular and cerebrovascular disease, immunologic disease, respiratory disease or kidney disease;
- •5. Patients with tumor, tuberculosis, rheumatism or rheumatoid arthritis, gout, joint trauma, or any other chronic pain symptoms, or with a history of brain injury with loss of consciousness;
- •6. Patients with MRI contraindications such as atresia phobia, pacemaker, defibrillator, cardiac stent, intrauterine device, etc..
Investigators
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