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A study about clinical effect of tuina manipulation in patients with knee osteoarthritis

Phase 1
Recruiting
Conditions
Knee Osteoarthritis
Registration Number
ITMCTR2000003043
Lead Sponsor
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Aged 40-65 years, men or women;
2. No massage or other related treatment was received in the last 4 weeks before the study;
3. Course of disease >= 3 months;
4. X-ray film (standing or weight-bearing position) shows joints Narrow space, subchondral bone sclerosis and / or cystic degeneration, osteophyte formation at the joint edge (satisfying any one of the X-ray characteristics);
5. With bone friction sound (sense) during movement;
6. With repeated knee pain history,
7. No Cancer, tuberculosis, or infection symptoms;
8. Have the ability and willingness to comply with interventions and follow-up assessments;
9. Volunteerly participate in this trial and sign informed consent;
10. No other treatment can be taken during the trial.

Exclusion Criteria

Participants who meet any of the following conditions will be excluded:
1. Have a history of knee trauma and surgery;
2. The onset of pain began in 3 months or before 2 years ago;
3. Received other massage therapy within 4 weeks before enrollment;
4. Have bone and joint tumors, tuberculosis, or infections seen in imaging;
5. Patients with severe diseases such as cardiovascular, cerebrovascular, hematopoietic, digestive system or mental illness;
6. People with abnormal liver and kidney function;
7. Pregnant and lactating women;
8. Other autoimmune diseases, allergic diseases and acute, Chronic infections;
9. Participate in other clinical trials.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Knee Injury and Osteoarthritis Outcome Score, KOOS;
Secondary Outcome Measures
NameTimeMethod
36-item Short-Form Health Survey, SF-36;McGill Pain questionnaire, MPQ;
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