Screening for esophageal second primary tumor in patients with head and neck cancer
Not yet recruiting
- Conditions
- Esophageal squamous cell carcinoma, head and neck cancer, second primary tumor, screening, Lugol chromoendoscopy
- Registration Number
- NL-OMON26998
- Lead Sponsor
- Erasmus Medical Center, Rotterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 600
Inclusion Criteria
HPV-negative oropharynx tumor
- Hypopharynx tumor
Exclusion Criteria
- Patient with a history of previous esophageal cancer
- Contraindication for endoscopy or biopsy (esophageal varices, major coagulation disorders which cannot be corrected)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The prevalence of synchronous esophageal second primary tumors in patients with head and neck squamous cell carcinoma
- Secondary Outcome Measures
Name Time Method 1. The prevalence of esophageal second primary tumors that can be curatively treated with minimally invasive endoscopic treatment or neoadjuvant therapy or surgery <br /><br>2. The prevalence of metachronous esophageal second primary tumors found during follow-up. <br /><br>3. The proportion of adjusted treatment plans of the index head and neck squamous cell carcinoma in patients diagnosed with an esophageal second primary tumor <br /><br>4. 5-year survival rate