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临床试验/NCT03470558
NCT03470558已完成不适用

Role of Dietary Habits in Efficacy of Bariatric Surgery - Study A

Brigham and Women's Hospital1 个研究点 分布在 1 个国家目标入组 290 人开始时间: 2018年12月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
290
试验地点
1
主要终点
Change in BMI at 1-year post-surgical

研究概览

简要总结

The purpose of the study is to evaluate how dietary habits in the post-surgical year impact outcomes of bariatric surgery.

详细描述

The obesity epidemic is a major public health concern with a significant economic burden in the USA. Bariatric surgery is the most effective and durable weight loss treatment, with long-term cardiometabolic health benefits. Among different types of bariatric procedures, sleeve gastrectomy (SG) has become the most commonly performed in USA. While SG is expected to result in a 50-60% excess weight loss, inter-individual differences in weight loss are large and approximately 25% of patients can be considered poor weight-loss responders who either do not lose a substantial amount of weight or regain the lost weight afterwards. The mechanisms underlying this clinical variation remain unknown and interventions to improve on these outcomes critically lacking. Of interest, altered daily dietary habits are experienced by a substantial proportion of bariatric surgery candidates, raising the question whether such alterations may contribute to inter-individual differences in weight loss success. Therefore, the purpose of this study is to evaluate how dietary habits in the post-surgical year impact outcomes of bariatric surgery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
21 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Bariatric surgery (sleeve gastrectomy) patients

排除标准

  • Prior bariatric surgical procedures

结局指标

主要结局

Change in BMI at 1-year post-surgical

时间窗: Baseline and one year

Body mass index at one year after surgery compared to baseline

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Frank AJL Scheer, PhD

Professor of Medicine

Brigham and Women's Hospital

研究点 (1)

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