Therapeutic study of the proton- pump inhibitors resistant patients with Non-Erosive Reflux Disease

Not Applicable

• Conditions: on-Erosive Reflux Disease (NERD); Digestive System; Non-Erosive Reflux Disease (NERD)

• Registration Number: ISRCTN82345975
• Lead Sponsor: Shimane University, Second Department of Internal Medicine (Japan)

Brief Summary

Results article in https://pubmed.ncbi.nlm.nih.gov/22367114/ (added 19/07/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-10-11
• Study Completion: 2007-12-31
• Last Update Posted: 2 August 2021

Recruitment & Eligibility

• Sex: All
• Target Recruitment: 149

Inclusion Criteria

1. Aged 20 and over
2. Heartburn (more than 6 points diagnosed by the Japanese version of questionnaire for the diagnosis of reflux disease [QUEST])
3. Signed a study-specific informed consent form

Exclusion Criteria

1. Endoscopic esophagitis
2. Gastric and duodenal ulcers, stomach cancer, or acute gastritis
3. Known hypersensitivity to rebamipide
4. Catastrophic complications
5. Pregnancy or desire to become pregnant
6. Judged inappropriate for this study by the physicians

Study & Design

• Study Type: Interventional
• Study Design: Not specified