Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance

Not Applicable

Recruiting

• Conditions: Heart Rate Variability; Mental Fatigue; Behavioral Performance; Skin Conductance; Cognitive Fatigue
• Interventions: Other: Baseline; Other: Fatigue Manipulation

• Registration Number: NCT05011318
• Lead Sponsor: Nanyang Technological University

Brief Summary

This study aims to examine the effects of cognitive fatigue on heart rate variability and skin conductance and develop a machine learning model.

Detailed Description

We hypothesize that increased cognitive fatigue would vary as a function of heart rate variability and skin conductance. A machine learning model will be developed that predicts cognitive fatigue through these physiological responses (Lee et al., 2021). Individual differences (i.e., age, gender, caffeine and food intake, body mass index, skin temperature, sleep quality, baseline physiology and behavioural performance) will be examined and accounted for.

Study Timeline

• Study First Submitted: 2021-08-12
• Study First Submitted QC: 2021-08-12
• Study First Posted: 2021-08-18
• Study Start: 2021-08-25
• Status Verified: 2023-03
• Last Update Submitted: 2023-03-21
• Last Update Posted: 2023-03-23
• Primary Completion: 2023-05-15
• Study Completion: 2023-06-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 162

Inclusion Criteria

• Singapore-based
• Non-clinical
• 18-35years

Exclusion Criteria

• Individuals with hearing difficulties or failing to meet the minimal threshold for normal hearing
• Individuals with a history of ear, developmental, neurological, or psychiatric disorder

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Fatigue Manipulation	Fatigue Manipulation	-
Fatigue Manipulation	Baseline	-

Primary Outcome Measures

Name	Time	Method
Fatigue State Questionnaire	up to 5 mins after fatigue manipulation	Fatigue State Questionnaire Score
2-Back Task (Change)	during fatigue manipulation	Change in Reaction Time over time
Electrocardiograph (Change)	during fatigue manipulation	Change in Heart Rate Variability over time
Electrodermal Activity (Change)	during fatigue manipulation	Change in Skin Conductance Response over time

Trial Locations

Locations (1)

Cultural Science Innovations, Nanyang Technological University; 🇸🇬 Singapore, Singapore