NL-OMON31635
Completed
Not Applicable
Effects of a high-fat and a low-fat diet on early biomarkers of metabolic stress in blood and gene expression in the small intestine of healthy subjects - Effects of high-fat and low-fat diet on the gut
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- disturbed fat and glucose metabolism
- Sponsor
- niversiteit Maastricht
- Enrollment
- 10
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •age between 18 and 65 years
- •body mass index (BMI) between 18 and 30 kg/m2
Exclusion Criteria
- •\- BMI \<\= 18 and \>\= 30 kg/m2
- •\- Serum Total cholesterol \> 8\.0 mmol/L
- •\- Fasting glucose \> 7\.0 mmol/L
- •\- Use of any medication
- •\- Active cardiovascular diseases like congestive heart failure or recent (\<6 months) event (acute myocardial infarction, CVA)
- •\- Gastrointestinal diseases (like celiac disease, inflammatory bowel disease, irritable bowel disease and food allergies) or a history of any gastrointestinal disorders or complaints
- •\- Pre\-existing gallbladder disease
- •\- Diabetes mellitus
- •\- Familial hypercholesterolemia
- •\- Severe medical conditions that might interfere with the study such as epilepsy, asthma, COPD and rheumatoid arthritis.
Outcomes
Primary Outcomes
Not specified
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