Influence of a high-fat vs. carbohydrate-rich low-glycemic vs. carbohydrate-rich high-glycemic diet on metabolic regulation in male endurance athletes
Phase 3
- Conditions
- Metabolic adaptation (fat and carbohydrate metabolism) in healthy male endurance athletes
- Registration Number
- DRKS00015521
- Lead Sponsor
- Institut für Sport und SportwissenschaftUniversität Freiburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 30
Inclusion Criteria
Age between 18-50 years
- Performance of endurance sports (running, cycling, playing sports), which require a basic endurance (3 - 5 units/week, VO2max > 55 mL/kg/min)
- stable weight and nutritional behavior (mixed diet)
- willing to be randomized
- no contraindications vs. physical activity according to the guidelines of the ACSM
Exclusion Criteria
- exessive endurance sport (> 5 units / wk)
- maligne diseases in the past 5 years
- cardiac disease (eg, chronic heart disease, arrhythmia, valvular heart disease, arthritis, etc.)
- arterial hypertension (RRsyst> 200 mmHg and / or RRdiast> 105 mmHg) at rest
- presence of Insulin-Dependent Diabetes Mellitus (IDDM)
- presence of a lipid metabolism disorder
- regular use of medication
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - *Respiratory quotient (RQ) at rest (fasten in the morning)<br>- *RQ in a 10-minute aerobic test (LT + 20 watts)<br>- Respiratory quotient under load (VT, RCP)<br>- Lactate thresholds (VT, IAS)<br>- VO2peak or Wattmax each per kg of body weight<br>- *resting metabolism<br>- Glucose at rest (fasten) under exercise<br>- Fat mass determined by BIA (under standard conditions)<br>- Rate of Perceived Exertionn (RPE) using the Borg scale<br>- *VAS score for general mood, GIT discomfort and exercise tolerance<br><br>- Measurement: U1 (screening), U2 (initial examination), U3 (interim examination) and U4 (final examination)<br><br>- *Measurement only at U2 (initial examination), U3 (intermediate examination) and U4 (final examination)
- Secondary Outcome Measures
Name Time Method Exploratory assessment in of physiological parameters (maximum oxygen uptake (V?O2 peak), RER and submaximal metabolic inflection points (lactate threshold 1 [LT1] and lactate threshold 2 [LT2]) during incremental cycling test until exhaustion after ingestion of a carbohydrate-rich, low glycaemic test meal within 1 week after the final examination (study arm 1 and 2)