comparing circuit life between modified membrane and standard membrane in liver failure patients

Not Applicable

Recruiting

• Conditions: critical illness; liver failure; severe acute kidney injury; Renal and Urogenital - Kidney disease; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12619000788178
• Lead Sponsor: Austin Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-28
• Last Update Posted: 22 June 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Patients have liver failure and severe AKI requiring CRRT AND
2. Patients have contraindications for regional citrate anticoagulant
3. Patients have contraindications for systemic heparin
4. Patient who, in the judgment of the treating clinician, are expected to continue CRRT greater than or equal to 48 h

Exclusion Criteria

1. Patient age is < 18 years
2. Pregnancy
3. DNR (do not resuscitate) DNI (do not intubate) orders
4. Death is deemed imminent or inevitable during this admission, and either the attending physician, patient or substitute decision-maker is not committed to active treatment
5. Patient needs to receive systemic anticoagulation for other indications

Study & Design

• Study Type: Interventional
• Study Design: Not specified