The impact of preoperative oral antibiotics on the microbiome and microbiology of the colo
Not Applicable
- Conditions
- colorectal cancerCancer - Bowel - Back passage (rectum) or large bowel (colon)
- Registration Number
- ACTRN12624000748516
- Lead Sponsor
- Otago University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1.Patients undergoing elective colorectal resection with primary anastomosis – this includes open, laparoscopic, or robotic resections.
2.Above the age of 18
Exclusion Criteria
1.Emergency surgery
2.Allergy to metronidazole or neomycin
3.Has received antibiotics in the preceding month before first sample collection
4.Pregnancy
5.Inability to consent
6.Post-Randomisation exclusion: No anastomosis performed
7. Patients having surgery with a rectal anastomosis will have swabs 1 and 2 performed, but will be excluded from having swabs 3 and 4 done.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method