Interval Training Study in Psoriatic Arthritis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 67
- Primary Endpoint
- Patient global assesment (PGA)
Study Overview
Brief Summary
Psoriatic arthritis is a chronical inflammatory disease characterized by pain and reduced physical function. Patients have a higher risk of cardiovascular disease and a higher body mass index.
A pilot study in patients with rheumatoid arthritis has shown positive effect on inflammation after 12 weeks of high-intensity interval training.
The primary aim of this study is to determine whether high-intensity interval training affects the disease activity in psoriatic arthritis. This intervention is believed to result in benefits in terms of inflammation, body composition and risk factors for cardiovascular disease.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •fulfilling the CASPAR criteria of psoriatic arthritis
- •ability to exercise.
Exclusion Criteria
- •Inability to exercise
- •very high disease Activity
- •unstable ischemic cardiovascular disease
- •severe pulmonary disease
- •pregnancy
- •breastfeeding
- •drug- and alcohol addictions
Outcomes
Primary Outcomes
Patient global assesment (PGA)
Time Frame: Baseline, 3 months (right after intervention), 9 months
PGA is measured as a change between timepoints. PGA is registered by the patient on a visual analog scale.
Maximal oxygen uptake (VO2 max)
Time Frame: Baseline, 3 months (right after intervention), 9 months
The VO2 max is measured as a change between timepoints
Secondary Outcomes
- Total lean mass(Baseline, 3 months (right after intervention), 9 months)
- Total body fat(Baseline, 3 months (right after intervention), 9 months)