Intra-articular versus Intravenous Tranexamic Acid in total knee arthroplasty
Phase 3
- Conditions
- Osteoarthritis of kneeBlood Loss after Total Knee Arthroplasty.
- Registration Number
- IRCT20160809029286N3
- Lead Sponsor
- Joint Reconstruction Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 98
Inclusion Criteria
Total knee arthroplasty candidate patients
Surgery in Imam Khomeini Hospital
Not having a specific bleeding disorder
Not having any co-morbidity
Not having any cardiovascular diseases
Accept the terms of participation in the study voluntarily
Exclusion Criteria
Cardiovascular diseases
Any co-morbidity
Any bleeding disorders
Thromboembolie and stroke history
Not voluntary
Sensitivity to tranexamic acid
Revision TKA
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post-operative Hb to pre-operative Hb. Timepoint: Pre-operative, 24 hour post-operative, 48 hour post-operative, 72 hour post-operative. Method of measurement: With blood lab test and blood loss calculation with GOOD & NADLER formulae.
- Secondary Outcome Measures
Name Time Method Occurrence of vascular thrombosis, DVT, Stroke and embolism. Timepoint: At least two years Follow-up. Method of measurement: Physical exam and para-clinics.