Helicobacter pylori eradication from general practice: clinical benefits and health economics

Completed

• Conditions: Digestive system diseases: Peptic ulcer disease; Digestive System; Peptic ulcer disease

• Registration Number: ISRCTN57634776
• Lead Sponsor: HS R&D Regional Programme Register - Department of Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2004-01-23
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients aged 50-59 years from selected General Practice (GP) surgeries (including asymptomatic volunteers as well as patients with dyspepsia)

Exclusion Criteria

1. Severe mental illness
2. Severe medical illness that would make the subject unable to survive for two years
3. Allergy to proton inhibitors, clarythromycin or metronizadole
4. Unwillingness to abstain from alcohol whilst taking antibiotics
5. Pregnancy
6. Concomitant prescription of cisapride, warfarin, antihistamines or theophyllines

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Absence of dyspepsia at two years<br>2. NHS dyspepsia costs for two years after the intervention

Secondary Outcome Measures

Name	Time	Method
1. Dyspepsia subgroups<br>2. Quality of life<br>3. H. pylori eradication rates<br>4. Adverse events