Extended Work Schedules and Health: Role of Sleep Loss

University of Chicago1 site in 1 country49 target enrollmentJanuary 2003

ConditionsSleep

Overview

This study aims to determine whether abnormal bodily rhythms contribute to elevate the risk of diabetes, independently of the amount of sleep loss.

Registry

clinicaltrials.gov

Start Date

January 2003

End Date

September 2009

Last Updated

9 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Sponsor

Responsible Party

Sponsor

•normal healthy men and women between the ages of 21 years and 39 years (inclusive) with normal weight (i.e., body mass index under 28 kg/m2 in men, 27 kg/m2 in women)
•normal findings on clinical examination, normal results on routine laboratory tests, normal EKG, normal glucose tolerance test, negative pregnancy test for women
•no personal history of psychiatric or endocrine illness
•no personal history of sleep disorder, usual total sleep time of at least 7 hours
•only female volunteers with normal ovulatory cycles will be included

•subjects with irregular life habits (shiftworkers and subjects having traveled across time zones less than one month prior to the beginning of the baseline study)
•subjects taking any medication (including hormonal contraceptive therapy), and smokers are excluded
•subjects with significant sleep apnea (apnea index above 10) or significant arousal-associated periodic leg movements are excluded