Effect of Alveolar Minute Ventilation on Respiratory Gas Heat Content
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Airway Enthalpy
研究概览
简要总结
This is a single site, prospective, non-blinded, non-randomized, non-interventional study designed to evaluate the effect of changes in alveolar minute ventilation on the measurement of respiratory heat loss (enthalpy).
详细描述
This is a single site, prospective, non-blinded, non-randomized, noninterventional study designed to evaluate the effect of changes in alveolar minute ventilation on the measurement of respiratory heat loss (enthalpy). Each patient will serve as their own control. The study will enroll adult patients without cardiac or respiratory illness. It is designed to evaluate the effect of the ventilatory pattern (tidal volume, rate) on respiratory heat loss measured using the VQm™ monitor during standard intra-operative clinical care that requires positive pressure ventilation (PPV)
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age greater than 18 years
- •scheduled for an elective surgical procedure with an anticipated duration of more than 2 hours requiring general anesthesia and positive pressure ventilation using an endotracheal tube
- •patient status ASA 1, 2 or 3
- •no significant cardio-vascular or respiratory disease
- •supine surgical position
排除标准
- •Adults unable to give primary consent
- •age less than 18 years
- •pregnancy
- •prisoners
- •pre-existing cardiac or pulmonary disease
- •infusion of inotropic drugs
- •positive end expiratory pressure (PEEP) requirements >8 cm H2O
- •increased intra-abdominal pressure (e.g. planned surgical pneumoperitoneum or ascitis)
- •intra-operative patient position other than supine
结局指标
主要结局
Airway Enthalpy
时间窗: 12 months
This is a single site, prospective, non-blinded, non-randomized, non-interventional study designed to evaluate the effect of changes in alveolar minute ventilation on the measurement of respiratory heat loss (enthalpy) in Joules per minute.
次要结局
未报告次要终点