Comparison of ropivacaine versus dexmedetomidine or ketamine in modified PECS II block in patients undergoing breast surgery: A Randomized trial

Not yet recruiting

• Conditions: Malignant neoplasm of breast,

• Registration Number: CTRI/2020/02/023655
• Lead Sponsor: All india institute of medical sciences patna

Brief Summary

This study is one of its kind as it is the study to compare the efficacy of drugs in controlling post operative analgesia among the patient undergoing breast surgeries using PECS 2 block  till date there are studies done in PECS 2 block but not with ropivacaine.since our study is mainly focused on comparing dexmeditomidine and ketamine along with ropivacaine by taking ropivacaine alone as a control group and to determine the requirement of rescue analgesia in 48 hours post operatively

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-02-27
• Study Start: 2020-02-29

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 75

Inclusion Criteria

1. Female population aged between 18-65 years 2) ASA I & II 3) Patients undergoing breast surgeries.

Exclusion Criteria

• Patient refusal Patients with underlying severe cardio-pulmonary compromise Morbid obesity BMI more than or equal to 35 Chest wall infiltration Presence of malignant breast mass in the field of block performance Pregnancy,lactation, dementia.
• Allergy to Local Anesthetic or adjuvants, Patients already on prescribed oral opioid analgesics or psychotropic agents Post radiation status of breast or axilla.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the total duration of post-operative analgesia and requirement of first rescue	48 hours
analgesia by the patient using an adjuvant (dexmedetomidine or ketamine) with ropivacaine in PEC II block undergoing breast surgeries	48 hours

Secondary Outcome Measures

Name	Time	Method
To determine the total amount of intra operative and post-operative opioid consumption	To assess the nnumerical rating scale in 1,2,4,6,1,18,24,48 hours post operatively

Trial Locations

Locations (1)

All india institute of medical sciences; 🇮🇳 Patna, BIHAR, India

All india institute of medical sciences

🇮🇳Patna, BIHAR, India

Dr Rajnish Kumar

Principal investigator

7783865337

drraj76pmch@gmail.com