CTRI/2020/02/023655尚未招募不适用
Efficacy of dexmedetomidine and ketamine as an adjuvant with ropivacaine in PECS II block among the patients undergoing modified radical mastectomy/ breast conservation surgery: A Randomized double blind controlled trial
All india institute of medical sciences patna1 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2020年2月29日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- To compare the total duration of post-operative analgesia and requirement of first rescue
研究概览
简要总结
This study is one of its kind as it is the study to compare the efficacy of drugs in controlling post operative analgesia among the patient undergoing breast surgeries using PECS 2 block till date there are studies done in PECS 2 block but not with ropivacaine.since our study is mainly focused on comparing dexmeditomidine and ketamine along with ropivacaine by taking ropivacaine alone as a control group and to determine the requirement of rescue analgesia in 48 hours post operatively
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- Female
入选标准
- •Female population aged between 18-65 years 2) ASA I & II 3) Patients undergoing breast surgeries.
排除标准
- •Patient refusal Patients with underlying severe cardio-pulmonary compromise Morbid obesity BMI more than or equal to 35 Chest wall infiltration Presence of malignant breast mass in the field of block performance Pregnancy,lactation, dementia.
- •Allergy to Local Anesthetic or adjuvants, Patients already on prescribed oral opioid analgesics or psychotropic agents Post radiation status of breast or axilla.
结局指标
主要结局
To compare the total duration of post-operative analgesia and requirement of first rescue
时间窗: 48 hours
analgesia by the patient using an adjuvant (dexmedetomidine or ketamine) with ropivacaine in PEC II block undergoing breast surgeries
时间窗: 48 hours
次要结局
- To determine the total amount of intra operative and post-operative opioid consumption(To assess the nnumerical rating scale in 1,2,4,6,1,18,24,48 hours post operatively)
研究者
研究点 (1)
Loading locations...
相似试验
尚未招募
不适用
Comparison of ropivacaine versus dexmedetomidine or ketamine in modified PECS II block in patients undergoing breast surgery: A Randomized trialCTRI/2020/02/023655All india institute of medical sciences patna
尚未招募
不适用
Ketamine and Dexmedetomidine Comparative StudyPost Operative PainNCT06032624Sohag University50
尚未招募
不适用
A comparative study of ketamine and dexmedetomidine versus ketamine and fentanyl for intravenous sedation in children undergoing infraumbilical surgeries under spinal anaesthesiaCTRI/2022/10/046610Vijayanagar institute of medical sciences60
Unknown
3 期
The Use of Ketamine and Dexmedetomidine in Intensive Care SedationICU PatientsSedationNCT04096768Lebanese American University Medical Center394
已完成
不适用
The Effects of Two Anesthetic Drugs on Some Enzyme Levels in Patients Undergoing Lower Extremity SurgeryMalondialdehydeHeme OxygenaseC-Reactive ProteinNCT05950555Ataturk University90