Tissue activity of microorganisms in gum diseases
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2021/01/030226
- Lead Sponsor
- Dhayanand John Victor
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Be between 30 to 60 years of age
2.Fulfill the criteria for Severe Chronic Periodontitis, Moderate Chronic Periodontitis and Mild Chronic Periodontitis as per the 1999 Workshop for Classification of Periodontal Disease
3.Sites categorized as Severe Chronic Periodontitis are to have CAL of > 4mm and Probing Pocket Depth of > 6mm, with clinical signs of gingival inflammation
4.Sites categorized as Moderate Chronic Periodontitis are to have >2mm and <5mm of Clinical Attachment Loss, with pocket depth of > 4mm
5.Sites with Mild Chronic Periodontitis are to have CAL of 1-2mm with Probing Pocket Depth of ï?³3mm, with clinical signs of gingival inflammation
6.Healthy Sites are to have no Clinical Attachment Loss and no evident bleeding on probing
1.Patients with Diabetes Mellitus
2.Patients with history of previous periodontal surgery
3.History of antibiotic intake in the last six months.
4.Pregnancy and Lactation.
5.Patients who are smokers and pan- chewers.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evels of intra-tissue periodontal pathogensTimepoint: Baseline
- Secondary Outcome Measures
Name Time Method evels of pro imflammatory markers IL-1beta and TNFTimepoint: baseline