Physical Activity and Testicular Cancer - a Pilot Study: Feasibility and Effects of a Program Including Information, Counseling and a Physical Activity Program for Patients With Testicular Cancer During and After Chemotherapy

Oslo University Hospital1 site in 1 country13 target enrollmentDecember 2012

ConditionsTesticular Cancer

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Testicular Cancer
Sponsor: Oslo University Hospital
Enrollment: 13
Locations: 1
Primary Endpoint: Muscle strength, 1RM (one-repetition-maximum)
Status: Completed
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine the feasibility and effect of a program including information, counseling and an individualized physical activity program on physical and psychological health during and after chemotherapy in patients with testicular cancer. It is hypothesized that the patients are able to complete the intervention with individual adjustments.

Registry

clinicaltrials.gov

Start Date

December 2012

End Date

June 2013

Last Updated

11 years ago

Study Type

Interventional

Study Design

Single Group

Sex

Male

Investigators

Sponsor

Oslo University Hospital

Responsible Party

Principal Investigator

Lene Thorsen

PhD

Oslo University Hospital

Eligibility Criteria

Inclusion Criteria

•Seminoma/non-seminoma
•Stage II-IV
•3-4 BEP(bleomycin,etoposide and cisplatin)or 4 EP(etoposide and cisplatin)
•\> 18 years
•Capable of reading and writing Norwegian

Exclusion Criteria

•Conditions of a severity that contraindicate exercise without adjusted actions
•Mentally incompetent conditions
•Conditions of a severity that complicates the ability to participate in a supervised training program

Outcomes

Primary Outcomes

Muscle strength, 1RM (one-repetition-maximum)

Time Frame: Baseline (0 weeks), post-intervention (9-12 weeks) and follow-up (24 weeks)

Change in 1RM from baseline to post-intervention and follow-up

Secondary Outcomes

Cardio respiratory fitness (VO2max)(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
Metabolic disease markers (blood pressure, body mass index, glucose, high density lipoprotein cholesterol, triglycerides)(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
Body composition (Lean body mass and fat mass)(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
Work status(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
Myoglobin(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
C-reactive protein (CRP)(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
Creatinkinase (CK)(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
Anxiety and depression(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
Quality of life(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
Creatinkinase - MB (CK-MB)(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))
Fatigue(Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks))