Safety of Metformin in patients with Diabetes and Early renal failure
Not Applicable
- Conditions
- Health Condition 1: null- Type 2 diabetes mellitus with chronic kidney disease stage 3a and 3b
- Registration Number
- CTRI/2013/12/004194
- Lead Sponsor
- Dr Manish Rathi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Patients with Type 2 diabetes mellitus and CKD stage 3a and 3b whose blood sugar is not controlled with oral hypoglycemic agents other than metformin with or without insulin.
Exclusion Criteria
1)Patients with CKD stage 4 & 5
2)Acute kidney injury
3) Congestive cardiac failure
4)Liver failure
5)Alcohol abuse
6)Hypoxemia
7)Refusal to give consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum lactate and Liver function testTimepoint: At baseline, then at 2 weeks and then at 4, 8 & 12 weeks
- Secondary Outcome Measures
Name Time Method 1. Serum creatinine <br/ ><br>2. HbA1cTimepoint: 1. At baseline and then at 4, 8, 12 weeks <br/ ><br>2. At baseline and then at 12 weeks