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Clinical Trials/NCT02100059
NCT02100059CompletedNot Applicable

Motor and Sensory Deficits Following Partial Meniscectomy

Creighton University2 sites in 1 country60 target enrollmentStarted: October 2013Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
60
Locations
2
Primary Endpoint
Changes in quadriceps force output and voluntary activation

Study Overview

Brief Summary

To determine changes in thigh muscle function and knee pain after a partial meniscectomy surgery and to also determine the effects of applying electrical stimulation to the knee to determine if this improves thigh muscle function and decreases pain.

Detailed Description

The objective for this study is to determine the differences in corticospinal excitability and central sensitization of nociceptive pathways in individuals with a history of arthroscopic partial meniscectomy compared to healthy controls. Our central hypothesis is that quadriceps weakness following partial meniscectomy is due to higher levels of corticospinal excitability and central sensitization of nociceptive pathways, which can be modified with therapeutic interventions.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
15 Years to 65 Years (Child, Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Age 15-65
  • Arthroscopic partial meniscectomy with in the past 15 years

Exclusion Criteria

  • History of traumatic spine or lower extremity injury within the last 6 months
  • Previous adverse reaction to electrical stimulation (i.e. burns or hypersensitivity)
  • Cardiac pacemaker
  • Metal implants in head
  • Current pregnancy
  • Neurological disorders
  • History of seizures
  • Unable to give consent or understand the procedures of this study

Outcomes

Primary Outcomes

Changes in quadriceps force output and voluntary activation

Time Frame: Single Study Visit

Quadriceps activation will be estimated by utilizing the burst-superimposition technique on a maximum voluntary isometric contraction (MVIC) and during a resting condition.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (2)

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