Behavioral Treatment for Cocaine Dependent Women
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Cocaine Dependence
- Sponsor
- Yale University
- Enrollment
- 145
- Locations
- 2
- Primary Endpoint
- Cocaine abstinence
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
To compare the efficacy of Community Reinforcement Approach (CRA) and 12-Step Facilitation (TSF) counseling and of voucher based reward therapy (VBRT) and a yoked, non-contingent voucher control (VC) for the treatment of cocaine dependent pregnant women or women with young children.
Detailed Description
Subjects were randomly assigned to 1 of 4 treatment groups (CRA+VBRT, CRA+VC, TSF+VBRT, TSF+VC). VBRT voucher value increased for each successive cocaine-free urine sample obtained twice weekly during the 1st 12 weeks and was faded from the final earned value to $5 during the last 12 weeks. All subjects earned vouchers for attendance at scheduled twice weekly counseling sessions. Manual-guided CRA and TSF were provided by experienced clinicians.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Pregnant women meeting DSM IV criteria for cocaine dependence
- •Women meeting DSM IV criteria for cocaine dependence with custody of a young child
Exclusion Criteria
- •Opioid dependence
- •Psychosis
- •Severe depression
- •Current treatment with any anti-depressant or anti-psychotic medication
- •Medical instability
- •Inability to understand or read English
Outcomes
Primary Outcomes
Cocaine abstinence
Time Frame: 24 weeks
Secondary Outcomes
- Reduced HIV risk behavior(24 weeks)