CTRI/2024/05/067691已完成4 期
COMPARISON OF THE EFFECT OF INTRAVENOUS DEXMEDETOMIDINE ADMINISTERED AS BOLUS OR BOLUS PLUS INFUSION ON SENSORY AND MOTOR BLOCKADE AFTER SPINAL ANAESTHESIA IN LOWER LIMB SURGERIES- A PROSPECTIVE CONTROL STUDY
Drsai sanjana1 个研究点 分布在 1 个国家目标入组 222 人开始时间: 2025年1月15日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 222
- 试验地点
- 1
- 主要终点
- To check for Improved and prolonged sensory and motor blockade
研究概览
简要总结
To investigate the influence of administering a calculated dose of 1 µg/kg of dexmedetomidine intravenously either as a bolus (1 µg/kg) or as a bolus-plus-infusion (0.5 µg/kg each) on the sensorimotor effects following subarachnoid anesthesia given in L3- L4 space with 12.5 mg of hyperbaric bupivacaine for lower limb surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Lower limb orthopedic surgery done under spinal anesthesia.
排除标准
- •Asa 3 Cardiac disease Bradycardia Hemodynamic unstable Allergy to dexmedetomidine or local anesthesia.
结局指标
主要结局
To check for Improved and prolonged sensory and motor blockade
时间窗: Intraoperative and end of surgery and 2 hours iin PACU.
次要结局
- Prevention of intraoperative & postoperative shivering(30 mins postspinal,end of surgery & 1hour after surgery)
研究者
Drsai sanjana
Sri ramachandra medical college and hospital and research Centre
研究点 (1)
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