NCT02064361CompletedNot Applicable
High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation
University Hospital of Split4 sites in 2 countries10 target enrollmentStarted: February 1, 2013Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 10
- Locations
- 4
- Primary Endpoint
- Change from baseline values of number of circulating microparticles per microliter of blood
Study Overview
Brief Summary
The purpose of this study is to determine the impact of high intensity,anaerobic exercise, in the form of cycling, on SCUBA diving. Outcomes are determined by the quantification and subtype of circulating microparticles, complete blood counts, and the quantification of venous gas emboli, measured via transthoracic echocardiography, in the cardiac cavities.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Experienced divers (> 250 logged dives)
- •Physician clearance to dive
Exclusion Criteria
- •Prior incidence of decompression sickness
Outcomes
Primary Outcomes
Change from baseline values of number of circulating microparticles per microliter of blood
Time Frame: Prior to exercise, prior to diving, 15 and 120 minutes after surfacing
Secondary Outcomes
No secondary outcomes reported
Investigators
Zeljko Dujic
Professor Zeljko Dujic MD, PhD
University Hospital of Split
Study Sites (4)
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