跳至主要内容
临床试验/CTRI/2023/10/058755
CTRI/2023/10/058755招募中不适用

clinical and etiological profile of acute kidney injury in patients admitted to intensive care units

Dr Gnyanavi Sai Chittela1 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2023年10月26日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
400
试验地点
1
主要终点
clinical profile of patients with acute kidney injury in ICU patients

研究概览

简要总结

Need for study

acute kidney injury incidence corresponds to almost 50%of all cause ICU admissions. AKI can be transient , persistent or acute kidney disease . there are still research gaps in the various causes and outcome of various causes of acute kidney injury , especially in developing countries , as the causes are different in both developing and developed countries . AKI reversal is observed in 72.9%of all AKI patients .

the risk of in hospital mortality , and ICU mortality increases  with increased in lactate albumin ratio according to a study. Patients with higher lactate albumin ratio showed significant shorter survival time .

Description

patients are selected from ICU after they meet selection criteria for study . after taking written consent from the patient , data is collected including demographic  profile, clinical symptoms , comorbidities , biochemical and etiological profile of the patient are collected as part of the study . laboratory data is collected . initial serum lactate and serum albumin values were taken  from within 48 hrs of admission duration of stay was noted. the treatment information including hemodialysis  .

data is analysed  , lactate albumin ratio is calculated and analysed . patients are divided into 4 quartiles . mortality rates in relation to each quartile are analysed . patients are followed up till discharge and status at discharge noted. dialysis dependence is analysed . data is analysed using appropriate stastical methods used for analysis .

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Patients admitted to icu with acute kindey injury.

排除标准

  • 1.18years of age 2.Chronic kidney disease with end stage renal disease 3.Pregnancy 4.Chronic liver disease patients 5.Those on metformin 5.Malignancy.

结局指标

主要结局

clinical profile of patients with acute kidney injury in ICU patients

时间窗: at time of discharge

次要结局

  • -to accesses lactate albumin ratio in predicting mortality of patient(-dialysis dependence analyzed)

研究者

发起方
Dr Gnyanavi Sai Chittela
申办方类型
Other [self]

研究点 (1)

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