clinical profile of acute kidney injury

Recruiting

Conditions: Acute kidney failure,

Registration Number: CTRI/2023/10/058755

Lead Sponsor: Dr Gnyanavi Sai Chittela

Brief Summary: Need for study

acute kidney injury incidence corresponds to almost 50%of all cause ICU admissions. AKI can be transient , persistent or acute kidney disease . there are still research gaps in the various causes and outcome of various causes of acute kidney injury , especially in developing countries , as the causes are different in both developing and developed countries . AKI reversal is observed in 72.9%of all AKI patients .

the risk of in hospital mortality , and ICU mortality increases with increased in lactate albumin ratio according to a study. Patients with higher lactate albumin ratio showed significant shorter survival time .

Description

patients are selected from ICU after they meet selection criteria for study . after taking written consent from the patient , data is collected including demographic profile, clinical symptoms , comorbidities , biochemical and etiological profile of the patient are collected as part of the study . laboratory data is collected . initial serum lactate and serum albumin values were taken from within 48 hrs of admission duration of stay was noted. the treatment information including hemodialysis .

data is analysed , lactate albumin ratio is calculated and analysed . patients are divided into 4 quartiles . mortality rates in relation to each quartile are analysed . patients are followed up till discharge and status at discharge noted. dialysis dependence is analysed . data is analysed using appropriate stastical methods used for analysis .

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: All

Target Recruitment: 400

Inclusion Criteria

Patients admitted to icu with acute kindey injury.

Exclusion Criteria

1.18years of age 2.Chronic kidney disease with end stage renal disease 3.Pregnancy 4.Chronic liver disease patients 5.Those on metformin 5.Malignancy.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
clinical profile of patients with acute kidney injury in ICU patients	at time of discharge

Secondary Outcome Measures

Name	Time	Method
-to accesses lactate albumin ratio in predicting mortality of patient	-dialysis dependence analyzed

Trial Locations

Locations (1): Kasturba Hospital, Manipal
🇮🇳
Udupi, KARNATAKA, India
Kasturba Hospital, Manipal
🇮🇳Udupi, KARNATAKA, India
Dr Gnyanavi Sai Chittela
Principal investigator
9492294333
gnyanavi29@gmail.com