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Innovative approaches for cocaine pharmacotherapy using fMRI: the case of varenicline.

Conditions
cocaine addiction
Registration Number
NL-OMON22626
Lead Sponsor
AMC Amsterdam, The Netherlands
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Other
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

1. Male, age 18-60 years;

2. Current DSM-IV diagnosis of cocaine dependence, but recently detoxified and abstinent;

Exclusion Criteria

1. Currently dependent on any substance other than cocaine or nicotine;

2. History of depression that could be defined as even a single episode or recurrent episodes of depression, or depression necessitating hospitalization, or history of suicide attempt (see fotenote1);

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Does varenicline reduce craving to cocaine and/or impulsivity in human cocaine users?
Secondary Outcome Measures
NameTimeMethod
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