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Effects of additional inhaled tiotropium in relapsing polychondritis with airway involvement

Not Applicable
Conditions
Relapsing polychondritis
Registration Number
JPRN-UMIN000006950
Lead Sponsor
St. Marianna University School of Medicine Division of Respiratory and Infectious Diseases, Department of Internal Medicine
Brief Summary

We experienced that inhaled tiotropium showed a marked improvement in airway involvement for one patient. However, no significant effects were noted in 8 RP patients for dyspnea (MMRC), visual analog score (VAS) or pulmonary function tests (spirometry and impulse oscillometry), before and after inhaled tiotropium.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
20
Inclusion Criteria

Not provided

Exclusion Criteria

1) Glaucoma or benign prostatic hypertrophy 2) Use of other anticholinergic agents within 1 month 3) Refused informed consent 4) Pregnant, possibly pregnant, or lactating patients. 5) Severe lung cancer, COPD and pneumonia except for bronchial asthma patients. 6) Patients judged inappropriate by the doctor in charge. 7) Current smokers.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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