Is MRKH syndrome caused by intrauterine blood exchange between sex-discordant twins?
Completed
- Conditions
- MRKH syndrome
- Registration Number
- NL-OMON28058
- Lead Sponsor
- VU university medical centre
- Brief Summary
Human Reprod 2019. Low prevalence of male microchimerism in women with MRKH
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 96
Inclusion Criteria
Diagnosed with MRKH syndrome
-Age ≥ 18 years
Exclusion Criteria
none
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome is the difference in occurrence of microchimerism (with an extra male cell line) in MRKH patients vs. controls.
- Secondary Outcome Measures
Name Time Method The secondary outcome is the presence of chimerism in non-hematopoietic tissue (buccal cells) in MRKH patients.