A randomized comparative study of propofol consumption for achieving adequate bispectral index using intravenous dexmedetomidine versus fentanyl in patients undergoing laparoscopic abdominal surgery under general anesthesia at SMS medical college jaipur

This randomized comparative study aimed to evaluate the effect of intravenous Dexmedetomidine versus intravenous Fentanyl on Propofol consumption required to achieve an adequate Bispectral Index (BIS) in patients undergoing laparoscopic abdominal surgeries under general anesthesia. Patients were randomly assigned to receive either Dexmedetomidine or Fentanyl as an adjunct to Propofol-based anesthesia. The primary outcome was the total Propofol requirement to maintain a target BIS level. Secondary outcomes included hemodynamic stability and recovery profiles. The study found that Dexmedetomidine significantly reduced Propofol consumption compared to Fentanyl, suggesting it as a more effective adjunct for BIS-guided anesthesia in this surgical context.