跳至主要内容
临床试验/NCT03073629
NCT03073629终止不适用

Implementation of a Clinical Pathway to Improve Outcomes in Emergency Department Patients With Right Ventricular Failure

Indiana University2 个研究点 分布在 1 个国家目标入组 2 人开始时间: 2017年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
终止
入组人数
2
试验地点
2
主要终点
Unscheduled healthcare visits

研究概览

简要总结

Millions of Americans seek emergency care for acute shortness of breath, and many undergo computerized tomographic pulmonary angiography (CTPA) testing that is negative for acute disease. Management of patients with persistent shortness of breath despite normal testing continues to pose a challenge for clinicians. Right ventricular (RV) failure is a common cause of dyspnea that brings patients to the emergency department (ED), however, it is often not considered in the differential diagnosis, remains unrecognized, or patients are not properly followed up once diagnosed. Delays in diagnosis and management of RV failure are associated with poor outcomes. The investigators propose a novel clinical pathway, which entails identifying and enrolling patients with RV failure in the ED, then referring them to a specialized cardiovascular clinic where they will receive a standardized evaluation and management plan. Our hypothesis is that management of RV failure, through this pathway, will improve patient outcomes when compared to standard care. The primary outcome will assess 1-year unscheduled healthcare visits.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult patients > 18 years old,
  • with a non-significant CTPA scan (i.e. no acute disease), dyspnea PLUS an emergency physician performed echocardiogram with isolated RV failure OR CTPA scan with evidence of pulmonary hypertension OR comprehensive echocardiogram within 3 months of index hospital visit showing isolated RV dysfunction

排除标准

  • Currently being evaluated and/or treated for RV failure or PH,
  • those unable to have a comprehensive echocardiography performed,
  • those with indeterminate RV function OR LV dysfunction on comprehensive echocardiography, and
  • those patients with circumstances where they may be lost to follow-up (homeless, prisoner, severe psychiatric disorder, no reliable contact information).

结局指标

主要结局

Unscheduled healthcare visits

时间窗: 1 year

次要结局

  • Change in quality of life via the SF-36(1 year)
  • Mortality(1 year)
  • Hospital re-admissions(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Frances Russell

Assistant Professor of Emergency Medicine

Indiana University

研究点 (2)

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