Effect of General Anesthesia Method Chosen in Non-cardiac Surgery of Cardiac Risk Patients on Ischemia Modified Albumin and Heart-Type Fatty Acid-Binding Protein (H-FABP) Levels
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 70
- 主要终点
- comparing serum levels of heart fatty acid binding protein
研究概览
简要总结
To examine the effects of the general anesthesia method chosen in non-cardiac surgical operations of patients with cardiac risk on the levels of cardiac markers
详细描述
To examine the effects of the general anesthesia method chosen in non-cardiac surgical operations of patients with cardiac risk on the levels of cardiac markers like; serum levels of the Creatine Kinase, Creatine Kinase Myocardial Band, high sensitive troponin, heart-type fatty acid-binding protein, ischemia-modified albumin and albumin. And evaluate the effect of anesthesia method on haemodynamic.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Being 18 years or older
- •Getting a score of 2 and above according to the Lee cardiac index
- •Having a non-cardiac surgical procedure that will take at least three hours
- •ASA II or III
排除标准
- •Under 18 years old
- •Those who refused to participate in the study
- •Patients with chronic renal failure
- •Patients with creatinine value ≥ 1.5 mg/dl
- •Surgery that takes less than 3 hours
- •Patients with liver failure
- •Refusing to participate in the study
- •Being allergic to the drugs used
结局指标
主要结局
comparing serum levels of heart fatty acid binding protein
时间窗: intraoperative period
serum levels of heart fatty acid binding protein (in terms of mcg/L)
comparing serum levels of ischemia modified albumin
时间窗: intraoperative period
serum levels of ischemia modified albumin (in terms of IU/ML)
次要结局
- The effect of anesthesia method used in cardiac risk patients in terms of ephedrine consumption(intraoperative period)
研究者
Aysenur Dostbil
Clinical Professor
Ataturk University