Effect of General Anesthesia Method Chosen in Non-cardiac Surgery of Cardiac Risk Patients on Ischemia Modified Albumin and Heart-Type Fatty Acid-Binding Protein (H-FABP) Levels
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Anesthesia
- Sponsor
- Ataturk University
- Enrollment
- 70
- Primary Endpoint
- comparing serum levels of heart fatty acid binding protein
- Status
- Not Yet Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
To examine the effects of the general anesthesia method chosen in non-cardiac surgical operations of patients with cardiac risk on the levels of cardiac markers
Detailed Description
To examine the effects of the general anesthesia method chosen in non-cardiac surgical operations of patients with cardiac risk on the levels of cardiac markers like; serum levels of the Creatine Kinase, Creatine Kinase Myocardial Band, high sensitive troponin, heart-type fatty acid-binding protein, ischemia-modified albumin and albumin. And evaluate the effect of anesthesia method on haemodynamic.
Investigators
Aysenur Dostbil
Clinical Professor
Ataturk University
Eligibility Criteria
Inclusion Criteria
- •Being 18 years or older
- •Getting a score of 2 and above according to the Lee cardiac index
- •Having a non-cardiac surgical procedure that will take at least three hours
- •ASA II or III
Exclusion Criteria
- •Under 18 years old
- •Those who refused to participate in the study
- •Patients with chronic renal failure
- •Patients with creatinine value ≥ 1.5 mg/dl
- •Surgery that takes less than 3 hours
- •Patients with liver failure
- •Refusing to participate in the study
- •Being allergic to the drugs used
Outcomes
Primary Outcomes
comparing serum levels of heart fatty acid binding protein
Time Frame: intraoperative period
serum levels of heart fatty acid binding protein (in terms of mcg/L)
comparing serum levels of ischemia modified albumin
Time Frame: intraoperative period
serum levels of ischemia modified albumin (in terms of IU/ML)
Secondary Outcomes
- The effect of anesthesia method used in cardiac risk patients in terms of ephedrine consumption(intraoperative period)