Quantification of Human Adipogenesis

Completed

• Conditions: Healthy
• Interventions: Biological: 15N-Thymidine, 2H-Water

• Registration Number: NCT01257997
• Lead Sponsor: Brigham and Women's Hospital

Brief Summary

This pilot study is using a novel technology to measure the rate of turnover of new fat cells. Analysis of volunteer samples is ongoing, however the study is currently not enrolling new volunteers.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12
• Study First Submitted: 2010-12-09
• Study First Submitted QC: 2010-12-09
• Study First Posted: 2010-12-10
• Primary Completion: 2016-12
• Study Completion: 2017-01
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-25
• Last Update Posted: 2018-01-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Aged 18-49 years.
• Healthy.

Exclusion Criteria

• Significant chronic medical illness.
• Illicit substance or alcohol abuse.
• Body mass index > 27 kg/meters squared.
• Underweight (BMI < 20 kg/m2).
• History of keloid formation (excessive scarring).
• Pregnant.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Healthy subjects	15N-Thymidine, 2H-Water	18-49 year old healthy men and women. Free of significant chronic medical illness and illicit substance abuse. Body mass index from 20 to 27.

Primary Outcome Measures

Name	Time	Method
Quantifying human adipogenesis-counting the number of new fat cells.	4 weeks-7 months

Trial Locations

Locations (1)

Brigham and Women's Hospital; 🇺🇸 Boston, Massachusetts, United States